Directions to Hannibal, MO

The Mark Twain Boyhood Home & Museum is in downtown Hannibal, Missouri. 

Interpretive Center

TOURS

Interpretive Center

415 N Main St
Hannibal, MO 63401

Mark Twain Museum Gallery

Official Mailing Address

Mark Twain Museum

120 N Main St
Hannibal, MO 63401

“It certainly had wide celebrity… but I was aware that it was only the frog that was celebrated. It wasn’t I."

- Mark Twain’s Autobiography

From the East

Take Interstate 72 from Illinois. Take Exit 157 and follow the brown signs

From the West

Take US Highway 36. Take Exit 157 and follow the brown signs

From the North

Take US Highway 61 South. Take US Highway 36 East to exit 157 and follow the brown signs

From the South

Take US Highway 61 North. Take US Highway 36 East to exit 157 and follow the brown signs

Parking

There is no charge to park in any public parking areas downtown.

Vehicle Parking

There are several parking options for the Mark Twain Boyhood Home and Museum. 

  • The Interpretive Center parking lot at the corner of Main and North Streets.
  • City parking lots located at Main and Bird Streets or the 300 Block of Main Street.
  • On-street parking.
  • Parking lot behind the Mark Twain Museum Gallery off Center Street or Broadway.
  • Parking lot at the Riverfront area accessible from Center Street or Broadway.

NOTE: During festivals and major events, some of these areas are closed to public parking.

Bus Parking

Bus or RV parking is located at the base of Center Street just past the railroad tracks adjacent to the river. Buses may drop off people outside the Interpretive Center or Mark Twain Museum Gallery. There is also ample parking on the south main street outside the flood wall. This would be a short walk to the Mark Twain Museum Gallery.